Careful analysis of the crude reaction mixture revealed a substituted enamine as the primary product, which was hydrolyzed over silica gel to give a γ-keto ester as the final product. 通过对反应过程的跟踪分析,发现反应的最初产物是取代的烯胺,该烯胺中间体在硅胶柱层析过程中发生水解,生成γ-酮酯为最终产物。
Research Progress on Asymmetric Hydrogenation of β-Keto Ester β-酮酸酯的不对称加氢反应研究进展
Research Progress on Asymmetric Catalytic Hydrogenation of P-Keto Ester β-酮酯不对称催化氢化反应研究进展
The progress of fundamental research of hydrogenation of β-keto ester by microbiological catalyst and metal chiral catalyst in recent years are reviewed. 本文综述了近年来用微生物和金属手性催化剂催化氢化β-酮酯的基础研究进展。
Herein we reported a series of new concept chiral ligands to catalyze α-keto ester to obtain corresponding chiral aryl-α-hydroxyl ester. 本论文尝试了一系列新概念手性配体来催化芳基-α-酮酸酯以获得相应的手性芳基-α-羟基酸酯。